4-ALLYLPHENOL

CAS: 501-92-8 FLAVORING AGENT OR ADJUVANT

4-ALLYLPHENOL is a phenolic flavoring agent used to impart specific aromatic profiles in foods. It has been evaluated by international expert bodies for safety when used at current levels of intake.

What It Is

4-ALLYLPHENOL is a defined chemical substance classified as a flavoring agent or adjuvant used in food and beverage applications to contribute to aroma and taste. It is a substituted phenol with a propenyl side chain at the para position on the aromatic ring, giving it a characteristic aromatic profile. By chemical definition, it belongs to the class of phenylpropanoids, a group of organic compounds that are structurally related to naturally occurring plant constituents. The substance is known by a variety of other names, including chavicol, p-allylphenol, and p-hydroxyallylbenzene, which reflect historical and structural nomenclature variants. As a flavoring agent, 4-ALLYLPHENOL is used in food formulation to deliver specific sensory attributes associated with spice, herbal, or phenolic notes. Its role as an adjuvant refers to its function in enhancing or modifying other flavor profiles within complex mixtures. The compound is typically encountered as a clear to slightly colored liquid at room temperature, with a volatile aromatic character that makes it suitable for incorporation into flavors and extracts designed for baked goods, beverages, confectionery, and savory products. From a regulatory standpoint, 4-ALLYLPHENOL has been evaluated by international expert committees to determine its safety profile in food use. These evaluations focus on the chemical identity, exposure levels from intended uses, and toxicological data to support decisions on whether its use in food presents any safety concern under current conditions of use. Such evaluations are essential in informing national and regional regulatory frameworks, ensuring that flavoring agents like 4-ALLYLPHENOL are used in a manner consistent with consumer safety and industry standards. The Joint FAO/WHO Expert Committee on Food Additives (JECFA) has assessed this compound and provided conclusions regarding its safety when used as a flavoring agent, forming a basis for international understanding of its regulatory status and risk characterization. Evidence from JECFA indicates that, at levels of intake anticipated from its use as a flavoring, there is no safety concern, although the evaluation is conditioned on usage data that inform exposure estimates. This context frames its classification and acceptance in food applications around the world. Estragole, another structurally related compound, illustrates a different regulatory context where concerns regarding genotoxicity and carcinogenicity have influenced use recommendations, particularly in certain regions. Such differences underscore the importance of compound-specific data in regulatory deliberations and demonstrate that even closely related chemical structures can have distinct safety assessments and use conditions. These comparisons emphasize that structural similarity alone does not determine regulatory status, and comprehensive evaluations of toxicology and exposure inform safety conclusions. In practical formulation terms, 4-ALLYLPHENOL, anethole, and estragole each contribute unique aromatic qualities that suit different flavor design objectives. While 4-ALLYLPHENOL offers phenolic and spicy notes, anethole is known for its sweet, anise-like character, and estragole provides a different aromatic profile associated with sweet, herbal nuances. Flavorists often select among such compounds based on desired sensory outcomes and regulatory acceptability in target markets. Overall, comparing 4-ALLYLPHENOL with similar additives highlights both the diversity of flavoring agents available to food formulators and the nuanced regulatory landscapes that govern their use based on safety evaluations and intake considerations.

Safety & Regulations

FDA

  • Notes: Specific CFR allowance not identified from available authoritative sources for this compound; its use is typically governed under general flavoring substances frameworks.

EFSA

  • Notes: EFSA framework requires evaluation for listing in the Union list of flavorings; specific data for this compound were not located.

JECFA

  • Notes: JECFA concluded no safety concern at current intake levels but did not assign a numeric ADI on the d report.

Sources

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